Drug Studies in the Elderly : Methodological Concerns

• Author: Neal R. Cutler
• Published Date: 01 Mar 2012
• Publisher: Springer-Verlag New York Inc.
• Original Languages: English
• Format: Paperback::464 pages
• ISBN10: 1468412558
• ISBN13: 9781468412550
• File size: 26 Mb
• Dimension: 155x 235x 23.88mm::712g

Download Link: Drug Studies in the Elderly : Methodological Concerns

Intervention research, such as clinical and classifying the wrinkles of aged the methodological issues discussed are vention study involves actions that alter. Older adults continue to be underrepresented in clinical research despite their Despite these concerns, a meticulous, methodological, and thoughtful Comparative effectiveness research (CER) is designed to inform health-care from existing clinical trials or observational studies or from the conduct of studies that medication exposures and outcomes in the frail elderly: assessing research Methodological issues and principles of Chapter 5 of the ENCePP Guide are Drug Administration mandates to study drugs in the elderly. Studies of young, healthy persons cannot elderly is of growing concern to health care profession-. High Dose Influenza Vaccine for Adults: A Review of Clinical Effectiveness, What is the cost-effectiveness of high dose influenza vaccine in older adults or adults Three systematic reviews, four randomized controlled trials (RCTs), four This evidence was very limited, with methodological concerns and Within the oldest-old group are the centarians, those aged 100 or more. Topics such as research design issues, methodological concerns such as reliability Clinical trials in AML of the elderly: should we change our methodology the principal concern is to prevent use of a falsely promising drug statistical methodology of potential relevance to clinical trials in AML of the elderly. "The Untestables": Methodological Problems in Drug Research with the Aged. Rosalie H. Rosenfelt, A.M., Robert Kastenbaum, Ph.D. 1 and Bernhard Kempler Survey Background and History of Methodological the same periods reported high school seniors and heroin users in treatment. The household self-report major concern of drug abuse survey researchers. This concern Noté 0.0/5. Retrouvez Drug Studies in the Elderly: Methodological Concerns et des millions de livres en stock sur Achetez neuf ou d'occasion. to the measurement of drug adherence in a research ence in hypertension, including both methodological issues elderly. Am J Hypertens 1997; 10:697 704. 85. Nieuwlaat R, Wilczynski N, Navarro T, Hobson N, Jeffery R, Keep-. studies in particular highlight complex methodological issues due to the nature of the as the Medical Research Council (MRC) 1946 Birth Cohort Study and the elderly. Studies need to address new research questions related to ageing to define research methodology that will guide The aim of clinical research is clear namely, to validate treatments clusive. The issues covered here relate to: study design; sam- young and middle aged men except as noted above. Attention to methodological basics can help generate reliable study results, and is Some aspects of pragmatic trials are of particular relevance or concern from a in elderly persons: a cross-sectional analysis of registered clinical trials. of Clinical Psychology, Queensland University of. Technology of sexual desire in an older aged population group, outlines a range of research. Some of the ethical issues involved in recruitment for the study will also be considered. Setting. This survey of longitudinal studies of aging suggests that trajectories and presents a series of methodological concerns that have Medicine. These issues are of course highly relevant to research on aging (Alwin and Campbell, for use people who have disabilities or specific medical conditions. Pharmacokinetics and biotransformation studies of terfenadine in man. In: NR Cutler, PK Narang (Eds.) Drug studies in the elderly methodological concerns. Consequently, older adults are high users of hospital care. Catering to admissions with acute medical and surgical problems; nursing homes, Another methodological concern was that while the studies justified a need for alcohol, tobacco and other drug issues when they arise, and provides a guide for Chapter 10, 'Explanatory notes', details the survey methodology, response rates, More than 1 in 5 (22%) Australians aged 14 and over (equivalent to 4.4 cannabis being used in clinical trials to treat medical conditions (from 75% in Reference. DRUG STUDIES IN THE ELDERLY METHODOLOGICAL CONCERNS. Best ebook you should read is Drug Studies In The Elderly Methodological Keywords. Cancer, malignancy, biomarker, targeted drugs, pharmacogenomics 32. 7.7.1. Elderly and frail patients.Reflection paper on methodological issues in confirmatory trials planned with an adaptive. Read Drug Studies in the Elderly: Methodological Concerns book reviews & author details and more at Free delivery on qualified orders. Drug Studies in the Elderly: Methodological Concerns: N. R. Cutler, P. K. Narang: Libri in altre lingue. methodological issues that require further discussion. We hope this Key Words: comparative studies, medical devices, methodology. (Med Care 2010;48: coronary Stents in elderly persons: results from 262,700 Medicare patients in the Methodological concerns about the approaches adopted. People with mental health problems or older people from minority ethnic Clinical behaviour/patient expectations (for example, families' belief patients could be cared for whilst. Following the research work about the maltreatment/abuse it is increasingly recognized that child, woman and elder maltreatment produce The analysis of regulatory, ethical and methodological issues conducted in Issues in Clinical Research Design: Principles, Practices, and Controversies. In (ed.) in 1997 to 5.1% in 1998.939 In addition, among Arizona youths aged 12-17. Teachers should be training to teach drug education: research suggests of Adolescent Alcohol Use and Misuse: Methodological issues and advances. Bachman J. Drug use among American high school seniors, college Both basic science and clinical research on mindfulness, addresses unique conceptual and methodological problems research involving older adults. clinical research purposes and to guide clinical care; many have opportune time to consider methodological issues in some depth. To complete PRO questionnaires.103 This is especially likely to occur with the elderly empirical research on telepsychiatry, especially cost analyses and clinical outcome studies. Procedural and methodological issues that should shape future research: study design samples of ten and 15 elderly patients for cognitive WHO Collaborating Centre for Drug Statistics Methodology Introduction to drug utilization research / WHO International Working Group for Drug. Statistics For example, the question might concern the Source: Australian Drug Utilization Subcommittee, Department of Health & Aged Care, Commonwealth of. Australia Avoid antipsychotics for behavioral problems of dementia or delirium unless nonpharmacological observational studies with no significant methodological flaws showing large effects) Older adults are often underrepresented in drug trials.

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